Frankincense, often hailed as the "King of Oils," has been treasured for millennia across various cultures for its aromatic allure and profound historical uses. Today, doTERRA offers
Frankincense Capsules, a convenient way to harness benefits associated with this remarkable botanical combining both resin and essential oil. But what exactly is behind its properties, and what does modern science reveal about its active components, particularly from the Boswellia resin?
The Science Behind Boswellia Resin and its Essential Oils
Frankincense is derived from the resin of trees belonging to the Boswellia genus, predominantly Boswellia sacra, Boswellia serrata, and others. The resin, a sticky sap that hardens into "tears," contains a complex array of compounds, including volatile essential oils and a group of powerful triterpenoids known as boswellic acids.
Boswellic Acids: Supporting a Healthy Inflammatory Response
Much of frankincense's documented efficacy is attributed to its boswellic acids, particularly Acetyl-11-keto-beta-boswellic acid (AKBA). These compounds are extensively researched for their influence on the body's natural inflammatory processes. Unlike many conventional approaches that may target cyclooxygenase (COX) enzymes, boswellic acids primarily inhibit 5-lipoxygenase (5-LOX). This enzyme is crucial in the biosynthesis of leukotrienes, which are mediators that contribute to inflammatory responses within the body.
- Supports Healthy Inflammatory Responses: Research suggests that boswellic acids can significantly modulate inflammatory pathways by inhibiting the production of certain inflammatory mediators and influencing immune cell activity.
- Promotes Joint Comfort and Mobility: Studies, particularly on Boswellia serrata extract, indicate its potential to support joint comfort and flexibility. Research suggests that boswellic acid extracts can help reduce occasional discomfort and improve physical function by supporting cartilage integrity and a healthy inflammatory response within joints.
- Supports Digestive Health: The modulating effects of boswellic acids extend to the digestive tract. Studies have shown promising results in supporting overall gut function and a healthy response to inflammatory challenges in the digestive system.
- Supports Respiratory Function: Traditionally used for respiratory support, scientific investigation suggests that frankincense compounds may help maintain clear airways and support a healthy respiratory system by influencing natural inflammatory processes.

Frankincense Essential Oil: More Than Just Aroma
While boswellic acids from the resin are largely associated with systemic wellness benefits, the essential oil distilled from the resin also offers distinct properties. Frankincense essential oil contains various monoterpenes and sesquiterpenes, with alpha-pinene being a prominent component in Boswellia sacra.
- Supports Healthy Cellular Function: Preclinical research suggests that frankincense essential oil may support healthy cellular function and renewal, potentially influencing healthy cell cycles.
- Promotes Healthy Skin Appearance: Historically used in skincare, the essential oil is believed to help maintain healthy skin structure and may offer antioxidant benefits.
- Supports Neurological Health: Some preclinical studies hint at potential protective effects on the nervous system and offer support against oxidative stress.
doTERRA's Frankincense Capsules a.k.a Boswellic Acid Complex, typically combining both the frankincense essential oil and a standardized extract of frankincense resin. By standardizing the extract to a high concentration of AKBA (e.g., 60%), these capsules aim to deliver a consistent and potent amount of the key boswellic acids, maximizing their intended benefits.
Important Considerations: Interactions with Medical Conditions and Medications
While frankincense (Boswellia) in dietary supplement form is generally considered well-tolerated for most adults when used appropriately, it's crucial to be aware of potential interactions. Always consult with your healthcare provider before incorporating frankincense capsules into your regimen, particularly if you have existing medical conditions or are taking medications.
Potential Interactions:
- Anticoagulant and Antiplatelet Medications (Blood Thinners): This concern specifically relates to the boswellic acids found in the resin extract. Research indicates that boswellic acids can inhibit platelet aggregation and may interact with clotting factors. Therefore, individuals taking blood thinners such as warfarin (Coumadin®), aspirin, clopidogrel, or NSAIDs (Non-Steroidal Anti-Inflammatory Drugs like ibuprofen or naproxen) should use frankincense resin extracts with extreme caution or avoid them altogether, as they may increase the risk of bleeding. Frankincense essential oil, comprised of volatile terpenes, does not contain boswellic acids in significant amounts and is not typically associated with these direct blood-thinning effects.
- Immunosuppressants: Given that boswellia can influence immune system activity, it might theoretically affect the action of immunosuppressant medications (e.g., those used after organ transplants). More research is needed in this area, but caution is advised.
- Medications Metabolized by the Liver (Cytochrome P450 Enzymes): Some research suggests that boswellia may interact with certain cytochrome P450 enzymes (e.g., CYP2C19, CYP3A4, CYP2C9, CYP1A2, CYP2D6), which are responsible for metabolizing a wide range of medications in the liver. This could potentially alter the effectiveness or side effects of these medications by changing their levels in the bloodstream. If you are taking any medications that are metabolized by the liver, discuss this with your doctor.
- Other Anti-Inflammatory Medications: Due to its own properties that support a healthy inflammatory response, boswellia may have additive effects with other anti-inflammatory drugs, including NSAIDs. While this might seem beneficial, it could potentially increase the risk of mild side effects.
- Pregnancy and Breastfeeding: There is insufficient reliable information on the safety of frankincense in higher, supplemental doses during pregnancy and breastfeeding. Some sources suggest that boswellia may stimulate blood flow in the uterus and pelvis. Therefore, it is generally advised to avoid frankincense supplements during these periods.
- Digestive Discomfort: Although generally well-tolerated, some individuals may experience mild digestive side effects such as stomach discomfort, nausea, or diarrhea, particularly at higher doses.
- Medical Conditions:
- Bleeding Disorders: Due to the potential of boswellic acids to influence platelet aggregation, individuals with bleeding disorders should exercise caution.
- Liver Conditions: While generally considered safe when used as directed, individuals with pre-existing liver conditions should discuss the use of any new supplement, including frankincense capsules, with their healthcare provider.

doTERRA Frankincense Capsules offer a compelling natural option for those seeking to support their body's natural inflammatory response, joint comfort, gut health, and cellular well-being, leveraging the scientifically supported properties of boswellic acids and frankincense essential oil.
However, like all dietary supplements, it's essential to approach its use with informed awareness.
Always consult with your healthcare provider to ensure it's a safe and appropriate addition to your personal health regimen, especially when considering existing health conditions and medications.
Ready to embrace a holistic path to well-being for your entire family – paws and all? As a medical doctor specializing in integrative health, essential oils, and animal behaviour, I offer tailored
consultations designed to empower you and your beloved pets.
Discover the transformative power of essential oils and explore my
doctor-curated kits and bonuses to support your journey.
Follow On Social Media
Please remember: Information shared is for educational purposes and not a substitute for medical or veterinary advice. Always consult with a qualified professional for specific health concerns.
The statements in this blog post have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.